Postdoctoral Position in SAXS of biomolecules

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pau.bernado
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Postdoctoral Position in SAXS of biomolecules

#1 Post by pau.bernado » 2017.12.06 13:30

A 2-year post-doctoral position funded by the EpiGenMed Labex program is available to work in the “Highly Flexible Proteins” group lead by Pau Bernadó at the Centre de Biochimie Structurale (CBS) in Montpellier (France).

Project: The project focuses on the development of experimental and analytical tools for the interpretation of Small-Angle X-ray Scattering (SAXS) data measured on low affinity biomolecular complexes mainly involving disordered proteins. With a multidisciplinary focus, the candidate will adapt computational approaches that have been recently developed in the group to structurally characterize heterogeneous biomolecular systems using SAXS (see references below). These methodological developments will be applied to the study of flexible biomolecular complexes involved in DNA processing and signal transduction.

Candidate: The successful candidate should have a PhD in chemistry, biology or physics and a solid background in Small-Angle Scattering (SAS) of biomolecules and/or chemometric methods. The candidate should have experience in computer programing and/or MATLAB, knowledge on the main tools used for the molecular modelling of SAS data will be favourably considered.

Environment: The CBS is a dynamic research institute with an outstanding infrastructure covering all techniques for structural biology and biophysics including NMR, X-ray crystallography, cryo-electron microscopy, advanced fluorescence and super-resolution microscopes, single-molecule manipulation, molecular and cell biology, and high-performance computation.
Montpellier is a major biology area with a focus on basic research, biomedicine, plant biology and environmental science. Its science drive, the beauty of the region, its high quality of life, and the short commute to other major regional research areas (Paris, Barcelona, Toulouse, Marseille) make it an ideal destination for scientists from all over the world.

Application: Applications and informal queries about the project and the lab should be addressed to Pau Bernadó (pau.bernado@cbs.cnrs.fr). Interested candidates should send their CV, a cover letter describing their research interests and motivation, and the names of people willing to write a recommendation letter.

Some Related Publications of the Group:
Herranz-Trillo F, et al. Structure, 2017, 25, 5-15.
Cordeiro TN, et al. Nucleic Acids Research 2017, 45, 1501-1515.
Cordeiro TN, et al. Current Opinion in Structural Biology, 2016, 42, 15-23.
De Biasio A, et al. Nature Communications 2015, 6, 6439.

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