Reference for Rg (solution) larger than Rg (crystal)

[leehc]

I'm looking for references (research papers) that R_g of a protein determined by SAXS analysis (Guinier analysis or GNOM) is larger than calculated R_g from a protein crystal structure.

I think it is common that R_g of a protein in solution is larger than R_g of a protein in crystal (if protein conformations are expanded in solution).

And I also experienced this for some SAXS experimental data.
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Could you suggest any research papers that shows the result of "R_g^saxs > R_g^crystal"

Thanks,

[SaxsMax]

You may want to check this one:

http://www.embl-hamburg.de/biosaxs/repr ... n_1998.pdf