Contribution of Glycosylation to the Ab initio model

Calculation of SAXS and SANS profiles (CRYSOL, CRYSON), superposition of models (SUPCOMB, DAMAVER, DAMCLUST), database DARA
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Jahabla
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Contribution of Glycosylation to the Ab initio model

#1 Post by Jahabla » 2019.03.04 21:58

Hello,

I am wondering what is the overall experience with N-linked glycosylation contribution to the ab initio model - i.e. how much will be the glycan visible in the shape of the envelope. I am assuming that when the N-linked glycosylation is more or less flexible it wont be "visible" in the shape of the envelope, similarly to electron densities in high-resolution structures. But when the glycan is stabilized and rigid than it will be more significantly pronounced in the ab initio envelope.

Are these correct assumptions?

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